Trials / Completed
CompletedNCT05832996
Cool vs Room-temperature Artificial Tears
Randomized Controlled Study of Cooled Versus Room-Temperature Artificial Tears for Reducing Surface Irritation Following Intravitreal Injection
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 124 (actual)
- Sponsor
- University of Iowa · Academic / Other
- Sex
- All
- Age
- 18 Years – 105 Years
- Healthy volunteers
- Accepted
Summary
Background and Objective: To evaluate the efficacy of cooled versus room temperature artificial tears in reducing post intravitreal injection (IVI) ocular discomfort. Patients and Methods: Patients receiving IVI were randomized to either cooled or room temperature tears intervention groups. Both groups rated their ocular discomfort following IVI before intervention and again after administration of cooled or room temperature tears.
Conditions
- Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis)
- Central Retinal Vein Occlusion With Macular Edema
- Exudative Age-Related Macular Degeneration, Unspecified Eye
- Cystoid Macular Edema
- Ocular Surface Disease
- Dry Eye Sensation
- Eye Pain
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Refresh Plus Preservative-free Lubricant Eye Drops | Refresh Plus Preservative-free Lubricant Eye Drops at either 4 or 25 degree Celsius |
Timeline
- Start date
- 2022-03-01
- Primary completion
- 2022-07-01
- Completion
- 2022-07-06
- First posted
- 2023-04-27
- Last updated
- 2025-03-04
- Results posted
- 2025-03-04
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT05832996. Inclusion in this directory is not an endorsement.