Clinical Trials Directory

Trials / Completed

CompletedNCT05821179

Salivary LINC00657 as a Diagnostic Biomarker for Oral Squamous Cell Carcinoma

Status
Completed
Phase
Study type
Observational
Enrollment
36 (actual)
Sponsor
Fayoum University · Academic / Other
Sex
All
Age
20 Years – 70 Years
Healthy volunteers
Accepted

Summary

This study was designed to verify the role of salivary LINC00657 as a diagnostic marker in oral squamous cell carcinoma (OSCC) patients as compared to oral lichen planus (OLP) (as an example of oral potentially malignant lesions) and normal individuals, and to show its relation to miR-106a. A total of 36 participants were included.

Detailed description

This study was designed to verify the role of salivary LINC00657 as a diagnostic marker in oral squamous cell carcinoma (OSCC) patients as compared to oral lichen planus (OLP) (as an example of oral potentially malignant lesions) and normal individuals, and to show its relation to miR-106a. A total of 36 participants were included, subdivided into 3 groups: Group I: 12 patients diagnosed with OSCC. Group II: 12 patients diagnosed with OLP. Group III: 12 systemically free individuals with no oral mucosal lesions. statistical analysis and ROC analysis were performed

Conditions

Timeline

Start date
2022-01-01
Primary completion
2023-01-01
Completion
2023-02-25
First posted
2023-04-20
Last updated
2023-04-20

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT05821179. Inclusion in this directory is not an endorsement.