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Active Not RecruitingNCT05814549

A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)

A Study of Using Plasma Circulating Cell Free Human Papillomavirus Deoxyribonucleic Acid to Screen (cf HPV DNA) for HPV-Related Oropharyngeal Cancer

Status
Active Not Recruiting
Phase
Study type
Observational
Enrollment
9 (actual)
Sponsor
Memorial Sloan Kettering Cancer Center · Academic / Other
Sex
All
Age
45 Years
Healthy volunteers
Accepted

Summary

The researchers think that a blood test (NavDx®) may be able to identify cancer early by looking for circulating DNA from Human Papillomavirus/HPV. Circulating DNA are small pieces of genes that are released into the bloodstream. The purpose of this study is to find out whether using this blood test to test for HPV DNA will help detect HPV-related Oropharyngeal Cancer/OPC.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTNavDxEvaluation of HPV presence via NavDx (v1) at two (or three) timepoints o If one of the two blood samples is positive, the subject will have a third NavDx (v1) test approximately 1 month after the second timepoint. If the test is positive, the subject will move to surveillance phase.

Timeline

Start date
2023-03-31
Primary completion
2031-03-31
Completion
2031-03-31
First posted
2023-04-18
Last updated
2025-09-19

Locations

7 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05814549. Inclusion in this directory is not an endorsement.