Trials / Completed
CompletedNCT05797194
The Association Between SIRI and POD in Older Patients
The Potential Value of Systemic Inflammation Response Index on Postoperative Delirium in Older Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 116 (actual)
- Sponsor
- Changhai Hospital · Academic / Other
- Sex
- All
- Age
- 65 Years
- Healthy volunteers
- Not accepted
Summary
Postoperative delirium (POD) remains one of most common complication in elderly patients receiving surgery, which is characterized by acute and fluctuating change in the level of cognition and consciousness. Previous studies have shown that surgery and anesthesia-induced acute peripheral inflammation and neuroinflammation may lead to delirium after surgery. Systemic Inflammation Response Index (SIRI) is a more easily accessible and comprehensive inflammation marker derived from monocyte, neutrophil, and lymphocyte count, which has been investigated to assess the prognosis of cancer and infectious diseases. However, the relationship between SIRI and POD has yet to be investigated.
Conditions
Timeline
- Start date
- 2019-03-01
- Primary completion
- 2019-10-31
- Completion
- 2019-10-31
- First posted
- 2023-04-04
- Last updated
- 2023-04-04
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT05797194. Inclusion in this directory is not an endorsement.