NCT05788016

Developing an Opioid Taper Intervention Before Total Joint Arthroplasty

Developing and Testing an Opioid Taper Intervention Before Total Knee Arthroplasty: Phase 2 Intervention Development

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: University of Alabama at Birmingham · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to develop an pharmacist-led preoperative opioid taper intervention for patients undergoing total knee or hip replacement who are on chronic opioids before their surgery. The main questions it aims to answer are: * Is the intervention feasible and acceptable to patients? * Does the intervention result in a decrease in opioid dose during the preoperative period? Participants will meet with a clinical pharmacist, who will provide some basic education on pain and opioids, and will propose an opioid taper schedule. The pharmacist will then follow-up with the participant by phone each week until surgery to assess progress and adjust the taper as necessary.

Conditions

• Arthritis Knee
• Arthritis Hip
• Chronic Pain

Interventions

Type	Name	Description
BEHAVIORAL	opioid taper	The participant will attempt to taper their opioid dose by \~50% during the 4-6 week preoperative period

Timeline

• Start date: 2024-01-10
• Primary completion: 2026-07-01
• Completion: 2026-09-01
• First posted: 2023-03-28
• Last updated: 2025-05-29

Locations

1 site across 1 country: United States