NCT05787522

Clinical Validation of AI-Assisted Radiotherapy Contouring Software for Thoracic Organs at Risk

Prospective, Multicenter, Randomized Evaluation of the Performance and Clinical Applicability of AI-Assisted Radiotherapy Contouring Software for Thoracic Organs at Risk

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 500 (actual)
• Sponsor: Tianjin Medical University Cancer Institute and Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to evaluate performance and clinical applicability of AI-assisted radiotherapy contouring software (iCurveE) for thoracic organs at risk. The main question it aims to answer is: • Does AI-assisted contouring (AI contouring with manual modification) offer greater accuracy and time efficiency compared to manual contouring? After screening, the qualified participants' thoracic CT images will be anonymized and segmented using three methods: manual, AI (AI-only), and AI-assisted contouring. The researchers will compare the results generated by the three different contouring methods with the ground truth established by expert consensus, in order to evaluate both accuracy and time-related parameters

Conditions

• Lung Cancer
• Breast Cancer
• Esophageal Cancer

Timeline

• Start date: 2022-09-30
• Primary completion: 2023-07-27
• Completion: 2024-03-06
• First posted: 2023-03-28
• Last updated: 2026-02-12

Locations

1 site across 1 country: China