NCT05775354

Reviving Early Diagnosis of Cardiovascular Disease in the Utrecht Health Project

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,476 (estimated)
• Sponsor: UMC Utrecht · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The goal of this randomized trial is to compare the diagnostic yield of a screen-like early diagnosis strategy to usual primary care to detect coronary artery disease (CAD), atrial fibrillation (AF), heart failure (HF), and/or valvular heart disease (VHD) in community people aged 50-80 years who participate in the Utrecht Health Project. The diagnosis strategy consists of a questionnaire with questions related to symptoms suggestive of CAD, AF or HF, a focused physical examination, laboratory testing, electrocardiography, and echocardiography.

Conditions

• Coronary Artery Disease
• Atrial Fibrillation
• Heart Failure
• Valvular Heart Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Early diagnosis strategy	RED-CVD early diagnosis questionnaire, physical examination, laboratory testing, electrocardiography, echocardiography

Timeline

• Start date: 2023-11-01
• Primary completion: 2026-05-01
• Completion: 2026-10-01
• First posted: 2023-03-20
• Last updated: 2024-02-23

Locations

1 site across 1 country: Netherlands