Trials / Completed
CompletedNCT05764564
External Body Pressure in Heart Failure With Preserved Ejection Fraction
External Body Pressure and the Impact on Exercise in Heart Failure With Preserved Ejection
- Status
- Completed
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 27 (actual)
- Sponsor
- Duke University · Academic / Other
- Sex
- All
- Age
- 30 Years
- Healthy volunteers
- Accepted
Summary
The primary objective of the study is to test the impact of positive and negative body pressure on exercise capacity, symptoms, blood volume distribution and central cardiac hemodynamics in patients with heart failure and preserved ejection fraction. Aim 1 will study healthy volunteers and heart failure patients non invasively while Aim 2 will study heart failure patients invasively (intracardiac pressures).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Positive or negative pressure | Positive or negative pressure is applied via a closed chamber. |
Timeline
- Start date
- 2023-04-21
- Primary completion
- 2025-05-31
- Completion
- 2025-05-31
- First posted
- 2023-03-10
- Last updated
- 2026-01-29
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT05764564. Inclusion in this directory is not an endorsement.