Clinical Trials Directory

Trials / Unknown

UnknownNCT05753852

Open Label Extension of TUDCA-ALS Study

Open Label Extension Study to Investigate Long Term Safety, Tolerability and Efficacy of Tauroursodeoxycholic Acid in Patients With ALS Who Completed the TUDCA-ALS Study

Status
Unknown
Phase
Phase 3
Study type
Interventional
Enrollment
184 (estimated)
Sponsor
Humanitas Mirasole SpA · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study will provide extended access to patients and assess longer-term outcomes on patients who have completed the TUDCA-ALS study.

Detailed description

The TUDCA-ALS Open label extension study is designed to investigate long term safety, tolerability and efficacy of tauroursodeoxycholic acid in patients with ALS who completed the TUDCA-ALS study

Conditions

Interventions

TypeNameDescription
DRUGTauroursodeoxycholic AcidTauroursodeoxycholic acid (TUDCA) 250 mg capsules Doses: 4 capsules (1 g) twice daily 10-15 minutes after a meal Mode of administration: orally Duration: 18 months

Timeline

Start date
2021-10-25
Primary completion
2025-03-31
Completion
2025-03-31
First posted
2023-03-03
Last updated
2023-03-03

Locations

23 sites across 7 countries: Belgium, France, Germany, Ireland, Italy, Netherlands, United Kingdom

Source: ClinicalTrials.gov record NCT05753852. Inclusion in this directory is not an endorsement.