NCT05724537

Durability at 20 Years of Quadrangular Resection With Annular Plication for Mitral Regurgitation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 145 (actual)
• Sponsor: Michele De Bonis · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Degenerative mitral regurgitation (MR) due to prolapse of the posterior leaflet is the most common dysfunction of the mitral valve (MV) in the Western world and is nowadays treated with a variety of surgical techniques. Quadrangular resection combined with annular plication and annuloplasty, as originally described by Carpentier, has been the standard approach for many years, before sliding/folding plasty and artificial chordae gained larger popularity.However, very few studies have been published on thevery long-term results (up to 20 years) of quadrangular resection and annular plication, often reporting only freedom from reoperation rather than from recurrent MR. This study aims to evaluate the very long-term (20 years) clinical and echocardiographic results of this approach, which was used for many years at the beginning of our mitral repair program.

Conditions

• Mitral Valve Disease

Interventions

Type	Name	Description
PROCEDURE	Quadrangular resection and annular plication	Mitral regurgitation is treated removing the redundant tissue of the posterior leaflet, which is then reconstructed by sutures and plicating the posterior annulus

Timeline

• Start date: 2019-02-23
• Primary completion: 2019-03-15
• Completion: 2019-03-15
• First posted: 2023-02-13
• Last updated: 2023-02-13

Locations

1 site across 1 country: Italy