NCT05719818

Dental Care and Initiation of Anti-osteoporotic Therapy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 338 (actual)
• Sponsor: Centre Hospitalier Universitaire de Nice · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The initiation of bisphosphonate therapy for osteoporosis requires an assessment of the oral status to prevent the risk of osteonecrosis of the jaw. This recommendation is sometimes a hindrance to the initiation of treatment or may be responsible for a delay in treatment or even the failure to initiate treatment. However, in the case of a severe osteoporotic fracture (femoral or humeral neck fracture, vertebral fracture or pelvic fracture), treatment must be rapid because of the major risk of refracture in the short term (multiplied by 5 in the 2 years following the fracture). In the rheumatology department of the Nice University Hospital, the investigator team take care of patients with osteoporotic fractures either directly in hospital or referred by the orthopedics department as part of a care program. For these patients, the team perform an etiological assessment, bone densitometry and evaluation of the oral status with dental panoramic and tele-expertise to determine if there is an indication to perform surgical care before starting the treatment. Therefore, the investigator aimed to describe the number of patients requiring dental surgery befor the initiation of bisphosphonate or denosumab treatment before to introduce treatment for osteoporosis

Conditions

• Dental Condition
• Osteoporosis

Interventions

Type	Name	Description
DRUG	biphosphonates	Initiation of bisphosphonate therapy
PROCEDURE	Dental care	Surgical dental care

Timeline

• Start date: 2019-01-03
• Primary completion: 2022-01-04
• Completion: 2022-01-04
• First posted: 2023-02-09
• Last updated: 2023-02-09

Locations

1 site across 1 country: France