NCT05706831

Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases

Music Intervention and Transcranial Electrical Stimulation for Treating Neurological Diseases

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Istituti Clinici Scientifici Maugeri SpA · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients. The main questions it aims to answer are: * to evaluate the residual neuroplastic processes in DOC state related to music exposure * to determine the putative modulation of the aforementioned processes and the clinical outcome of DOC patients by non-pharmacological strategies, i.e., electric (tDCS) and music stimulation * to evaluate the impact of this intervention on caregiver's burden and psychological distress. Participants will be randomly assigned to one of three different music-listening intervention groups. Primary outcomes will be clinical, that is based on the neurologist's observations of clinical improvement, and neurophysiological, collected pre-intervention, post-intervention and post-placebo.

Conditions

• Disorder of Consciousness
• Stroke

Interventions

Type	Name	Description
OTHER	Combinatory effect of music stimulation and neurostimulation	music

Timeline

• Start date: 2022-09-01
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2023-01-31
• Last updated: 2025-06-04

Locations

1 site across 1 country: Italy