NCT05691335

Three Different Cross-linking Protocols for Treatment of Pediatric Keratoconus

Analysis of the Outcomes of Three Different Cross-linking Protocols for Treatment of Pediatric Keratoconus

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 97 (actual)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 12 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

comparison between standard cross-linking protocol and accelerated and transepithelial cross-linking

Detailed description

comparison between standard cross-linking protocol and accelerated and transepithelial cross-linking for treatment of documented pediatric keratoconus progression. The study patients are divided into 3 groups. Group A patient treated with standard cross-linking. Group B patients treated with accelerated cross-linking. Group C patients treated with transepithelial cross-linking.

Conditions

• Corneal Ectasia

Interventions

Type	Name	Description
PROCEDURE	Standard CXL	Epithelium-off CXL performed by removal of corneal epithelium, instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 30 minutes.
PROCEDURE	Accelerated CXL	Epithelium-off CXL performed by removal of corneal epithelium, instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 5 minutes.
PROCEDURE	Transepithelial CXL	Epithelium-on CXL performed by instillation of riboflavin onto the cornea followed by UVA corneal irradiation for 5 minutes.

Timeline

• Start date: 2018-06-01
• Primary completion: 2023-01-01
• Completion: 2023-01-05
• First posted: 2023-01-20
• Last updated: 2023-03-31

Locations

1 site across 1 country: Egypt