Trials / Completed
CompletedNCT05684133
REMISE Study: REMnant Biospecimen Investigation in SEpsis
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 71 (actual)
- Sponsor
- University of Pittsburgh · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
In the REMISE is study, we will compare blood proteins, biomarkers, and other -omics prospectively collected from patients with sepsis from two sources, i.) remnant (discarded) samples from the clinical laboratory, and ii.) prospectively collected in UPMC Presbyterian hospital research coordinator specimen collected biospecimens. Analyses will include traditional biomarkers, quantitative proteomics, metabolomics, lipidomics, transcriptomics, and pathogen genomic sequencing in both sets of samples. This data will allow the assessment of the feasibility, integrity, and scientific value of remnant samples compared to research coordinator samples collected at the bedside for mechanistic sepsis research.
Conditions
Timeline
- Start date
- 2022-10-25
- Primary completion
- 2023-12-31
- Completion
- 2023-12-31
- First posted
- 2023-01-13
- Last updated
- 2024-02-28
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05684133. Inclusion in this directory is not an endorsement.