NCT05673915

Study of Transcranial Direct Current Stimulation to Treat Epilepsy

Pilot Study of Transcranial Direct Current Stimulation (tDCS) to Treat Epilepsy

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 6 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic seizures.

Detailed description

tDCS for treatment of epilepsy has been studied previously with results suggesting that it can lead to a notable seizure reduction for a limited time period after the cessation of stimulation, e.g., about one month. Here, we assess further aspects of tDCS treatment protocols, including the feasibility and safety of at-home use.

Conditions

• Focal Epilepsy
• Generalized Onset Epilepsy
• Sleep-related Epileptic Encephalopathy

Interventions

Type	Name	Description
DEVICE	ActivaDose II 0.1 mA transcranial direct current stimulation (tDCS)	Stimulation setting 0.1 mA daily for a 2-month period. Each daily treatment will last for approximately 30 minutes.
DEVICE	ActivaDose II 2.0 mA transcranial direct current stimulation (tDCS)	Stimulation setting 2.0 mA daily for a 2-month period. A Each daily treatment will last for approximately 30 minutes.

Timeline

• Start date: 2023-04-12
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2023-01-06
• Last updated: 2026-01-28

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study