NCT05643963

The COOKER-BLADDER Trial

modifiCatiOn of fOod intaKe to Influence the Equilibrium of the uRinary BLADDER

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: Roland Seiler-Blarer · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The goal of this interventional study is to test the influence of food intake with characteristics of the urinary bladder. The main questions it aims to answer are: * How does food intake modify the characteristics of urothelial cells? * Does change of specific diet regimes influence biomarker characteristics in urine? Participants will follow specific diet regime for a given time period. After completion of this period biomarker assessment is performed. Thereafter the participants follow an opposite diet regime for the same time period with identical biomarker assessment at the end. Biomarkers within the participants and between the diet regimes will be compared to investigate the influence of food intake on the urinary bladder.

Conditions

• Diet, Healthy
• Urinary Bladder Diseases
• Oncogenesis

Interventions

Type	Name	Description
OTHER	Dietary regimens	Food intake will follow a recommendation according to a specific list. Protective and non-protective food intake will be performed for specific time periods with biomarker assessment after each period.

Timeline

• Start date: 2025-03-25
• Primary completion: 2025-12-02
• Completion: 2025-12-02
• First posted: 2022-12-09
• Last updated: 2025-12-11

Locations

2 sites across 1 country: Switzerland