NCT05642351

Autobiographical Specificity

Autobiographical Specificity in Alzheimer's Disease and Behavioral Variant Frontotemporal Dementia

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 39 (actual)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Autobiographical memory is diminished in patients with Alzheimer's Disease and those with behavioral variant of frontotemporal dementia, and research has focused on the hampered ability of patients in retrieving specific memories. However, this study proposes a detailed methodology to provide a qualitative analysis of autobiographical specificity.

Detailed description

Patients with Alzheimer's Disease and those with behavioral variant of frontotemporal dementia will be invited to retrieve autobiographical memories. Memories will be analyzed and categorized into specific, categoric, extended, or semantic autobiographical retrieval.

Conditions

• Memory
• Alzheimer Disease
• Frontotemporal Dementia

Interventions

Type	Name	Description
OTHER	Autobiographical reminder	The analysis of the specificity of Autobiographical Recall will be done through the following scale, developed for the study: * 6 points for a recall involving a single personal event located in space AND time (e.g.,"I remember when my parents took me to the sea for the first time..in 1962..in Dunkerque") * 5 points for a recall involving a single personal event located in space OR time ("I remember when my parents first took me to the sea...in 1962") * 4 points for a recall involving a single personal event but without spatial/temporal details ("I remember when my parents took me to the sea for the first time") * 3 points for a recall involving a general personal event but located in space AND time ("we used to go to Dunkerque in the summer") * 2 points for a recall involving a general personal event but located in space OR time ("we used to go to Dunkerque") * 1 point for a recall involving a general personal event without spatial/temporal details ("we used to go on vacation")

Timeline

• Start date: 2023-02-03
• Primary completion: 2026-03-06
• Completion: 2026-03-06
• First posted: 2022-12-08
• Last updated: 2026-04-03

Locations

1 site across 1 country: France