NCT05604651

Comparison of Mucin Levels at the Ocular Surface of Visual Display Users With and Without Dry Eye Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 94 (actual)
• Sponsor: Peking University Third Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The study aimed to evaluate 1) if levels of the glycocalyx membrane mucins, including MUC1, MUC4, MUC16 and MUC20, are altered in conjunctival cells of visual display users With and Without Dry Eye Disease, and 2) if mucin levels correlate with dry eye clinical diagnostic data.

Detailed description

The cross-sectional study aimed to evaluate 1) if levels of the glycocalyx membrane mucins, including MUC1, MUC4, MUC16 and MUC20, are altered in conjunctival cells of visual display users With and Without Dry Eye Disease, and 2) if mucin levels correlate with dry eye clinical diagnostic data.

Conditions

• Dry Eye Disease

Interventions

Type	Name	Description
OTHER	no intervention	no intervention

Timeline

• Start date: 2021-03-01
• Primary completion: 2021-09-02
• Completion: 2021-09-02
• First posted: 2022-11-03
• Last updated: 2022-11-23

Locations

1 site across 1 country: China