NCT05602688

Melissa Officinalis L. Supplementation for Emotional Health and Sleep Disturbance

Study to Investigate Melissa Officinalis L. Supplementation for Emotional Health and Sleep Disturbance: A Perspective, Randomized, Double-blinded, Placebo-controlled, Parallel-group Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 102 (actual)
• Sponsor: Ayub Teaching Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This study is aimed to investigate if Lemon Balm Extract supplementation is beneficial for the relief of stress, depression and anxiety in healthy adults.

Detailed description

Lemon balm (Botanical name: Melissa officinalis L.) is a herbal plant belongs to the Lamiaceae (mint) family, and currently of wide scientific interest as possible adjuvant for calming effect. Lemon balm is one of the most popular and widely used medicinal herbs in central and southern Europe, the Mediterranean region, and west Asia. The European Scientific Cooperative on Phytotherapy (ESCOP) recommends the use of lemon balm to relieve of mild symptoms of anxiety, including mental stress, restlessness, and irritability. Historically, Lemon balm has been widely used in Asian traditional medicine as a sedative to treat many psychiatric disorders, such as stress, depression, anxiety, and insomnia. Lemon balm has shown anti-depressant, anxiolytic, and anti-insomnia effects both in human clinical trials and in animal model studies.

Conditions

• Depression
• Anxiety
• Stress
• Insomnia

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Lemon Balm Supplement	Oral 200 mg Lemon Balm supplement tablet Twice a day for three-weeks
DIETARY_SUPPLEMENT	Matched Placebo	Matched placebo tablet Twice a day for three-weeks

Timeline

• Start date: 2023-01-03
• Primary completion: 2023-04-10
• Completion: 2023-04-30
• First posted: 2022-11-02
• Last updated: 2023-05-31

Locations

1 site across 1 country: Pakistan