NCT05584878

Remineralizing Potential of Biomimetic Scaffolds on Enamel White Spot Lesions

Clinical and Topographic Evaluation of the Remineralizing Potential of Biomimetic Scaffolds on Enamel White Spot Lesions (a Randomized Controlled Clinical Trial and In-vitro Study)

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 63 (estimated)
• Sponsor: Hams Hamed Abdelrahman · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

The modern concept in caries treatment focuses on the non-invasive approach and on the biomimetic remineralization of early non-cavitated white spot carious lesions. Recently developed biomimetic scaffolds attempt to remineralize the dental tissues and are more regenerative than reparative.

Conditions

• White Spot Lesion

Interventions

Type	Name	Description
OTHER	Curodont repair Self- assembling peptide P11-4	The labial surface of each tooth in both arches from central to the first premolar on both sides will be treated by Curodont
OTHER	Ph-chi phosphorylated - nano-chitosan	The labial surface of each tooth in both arches from central to the first premolar on both sides will be treated by Ph-chi phosphorylated - nano-chitosan
OTHER	CCP-ACP " +ve control " Casein phosphopeptide amorphous calcium phosphate	The labial surface of each tooth in both arches from central to the first premolar on both sides will be treated by CCP-ACP

Timeline

• Start date: 2023-01-01
• Primary completion: 2024-01-30
• Completion: 2024-01-30
• First posted: 2022-10-18
• Last updated: 2022-10-18

Locations

1 site across 1 country: Egypt