NCT05569525

Type I Diabetes and Non-surgical Periodontal Treatment

Effects of Non-surgical Periodontal Therapy on the Glycemic Variability of Periodontal Patients Affected by Type I Diabetes. a Randomized Clinical Trial.

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of Florence · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Current evidence suggests a bidirectional association between periodontitis and diabetes. Periodontal therapy improves short term HbA1c levels and is safe to perform. Most studies are focused on type 2 Diabetes. Literature about the correlation between periodontitis and type 1 diabetes is scarce, since no randomized clinical trials have been performed. The objective of the present clinical investigation is to evaluate the effects of nonsurgical treatment of periodontal disease on glycemic variability in patients with type 1 diabetes (T1DM). The hypothesis is that nonsurgical periodontal therapy affects glycemic variability in terms of time spent in hyperglycemia.

Conditions

• Type 1 Diabetes
• Periodontitis
• Periodontal Diseases
• Diabetes
• Diabetes Mellitus
• Diabetes Mellitus, Type 1

Interventions

Type	Name	Description
PROCEDURE	Non-surgical periodontal therapy	Non-surgical periodontal therapy according to the full-mouth debridement protocol.

Timeline

• Start date: 2022-11-06
• Primary completion: 2023-11-10
• Completion: 2025-12-10
• First posted: 2022-10-06
• Last updated: 2024-12-06

Locations

1 site across 1 country: Italy