NCT05560789

The Effect of Physical Activity in Individuals With Post-bariatric Hypoglycemia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: Joslin Diabetes Center · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The goal of this pilot study is to evaluate the magnitude of changes in glucose and hormone levels in response to structured exercise in the fasting state in individuals with post-bariatric hypoglycemia (PBH). This pilot study will assess the adequacy of a protocol to test the following hypotheses: (1) hypoglycemia will develop in individuals with PBH in response to exercise; (2) counterregulatory hormonal responses to hypoglycemia during exercise are impaired in individuals with PBH.

Conditions

• Hypoglycemia
• Roux-en-Y Gastric Bypass
• Post-bariatric Hypoglycemia
• Physical Activity

Interventions

Type	Name	Description
BEHAVIORAL	Physical activity (cycling on a stationary bicycle ergometer or walking on a treadmill)	At time 0, exercise will be initiated and intensity will be increased at 2 minute intervals to achieve low intensity for 30 minutes (as defined by heart rate target 50-55% of maximum heart rate determined as 220-age). Next, intensity will be increased at 2 minute intervals until the heart rate target for moderate intensity exercise is achieved (55-65% of max heart rate), or the total duration of exercise of up to 60 minutes is achieved.

Timeline

• Start date: 2023-01-03
• Primary completion: 2024-03-22
• Completion: 2024-03-22
• First posted: 2022-09-29
• Last updated: 2024-04-08

Locations

1 site across 1 country: United States