Clinical Trials Directory

Trials / Completed

CompletedNCT05553366

Evaluation of Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy

A Phase 3, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
1,075 (actual)
Sponsor
Vertex Pharmaceuticals Incorporated · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of suzetrigine for acute pain after a bunionectomy.

Conditions

Interventions

TypeNameDescription
DRUGSUZTablets for oral administration.
DRUGHB/APAPCapsules for oral administration.
DRUGPlacebo (matched to SUZ)Placebo matched to SUZ for oral administration.
DRUGPlacebo (matched to HB/APAP)Placebo matched to HB/APAP for oral administration.

Timeline

Start date
2022-10-03
Primary completion
2023-12-15
Completion
2023-12-15
First posted
2022-09-23
Last updated
2025-08-01
Results posted
2025-08-01

Locations

21 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05553366. Inclusion in this directory is not an endorsement.