NCT05521386

The Effects of Caffeine on Heart Rate and Heart Rate Variability

The Effects of Caffeine Supplementation on Heart Rate and Heart Rate Variability at Rest and During Submaximal Exercise

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (estimated)
• Sponsor: St Mary's University College · Academic / Other
• Sex: Male
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

In previous research we have shown that an acute caffeine dose of 5 mg/kg body mass reduces heart rate at rest and during low intensity exercise, with the effect dissipating as exercise intensity increases. If, as suspected, the effect at rest and at low intensities is due to an effect of caffeine on parasympathetic activity, this is likely to be reflected in an increase in heart rate variability (the beat-to-beat fluctuation in heart rate). The aim of this study is therefore to investigate the effect of caffeine on heart rate and heart rate variability at rest and during submaximal exercise.

Conditions

• Caffeine

Interventions

Type	Name	Description
DRUG	Caffeine	Single pill in an acute dose of 5 mg per kg of body mass
DRUG	Placebo	Single pill in an acute dose of 5 mg per kg of body mass

Timeline

• Start date: 2022-09-01
• Primary completion: 2023-03-31
• Completion: 2023-04-30
• First posted: 2022-08-30
• Last updated: 2022-08-30