NCT05499806

Cohort Study on the Effects of Aging in Acquired Brain Injury Patients

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 800 (estimated)
• Sponsor: University Medical Center Groningen · Academic / Other
• Sex: All
• Age: 50 Years – 67 Years
• Healthy volunteers: Accepted

Summary

A prospective cohort study (questionnaires), with an embedded case control study (neuropsychological assessments) in which the data is gathered within a timeframe of 3 years. A group of 700 patients and a group of 100 healthy volunteers will be participating.

Detailed description

In the Netherlands an estimated 650.000 people live with the daily consequences of an Acquired Brain Injury (ABI). A substantial amount of these patients acquired their brain injury (traumatic brain injury, subarachnoid hemorrhage or cerebrovascular accident) at a relatively young age: between 18 and 50 years old. The chain-of-care for ABI aims for recovery in the subacute phase, usually within a period of one year after injury. After an adaptation period, the patients reach a new balance, with stabilization of complaints and reintegration, sometimes with the necessity of modifications. The group of patients who acquired a brain injury at a young age, have to face the effects of aging like decreased cognitive functions, which can cause the participation level to drop. This is called the ABI-effect in the current study. At this moment, insufficient information is available about the functioning of people who suffered ABI multiple years ago and have established a new balance, and now make the transition to an older phase of live. Primary objective: Explore the prevalence of the ABI-effect, by mapping the participation level. Secondary objective: Substantiate the occurence of the ABI-effect, by mapping cognitive functions of patients and compare these to healthy controls. Tertiary objective: Gain insight in the need of care for patients, to enhance regular care after ABI.

Conditions

• Acquired Brain Injury
• Subarachnoid Hemorrhage
• Traumatic Brain Injury
• Cerebrovascular Accident

Timeline

• Start date: 2022-03-18
• Primary completion: 2023-03-01
• Completion: 2024-02-01
• First posted: 2022-08-12
• Last updated: 2022-08-12

Locations

2 sites across 1 country: Netherlands