NCT05479474

Platelet Rich Plasma Testis Treatment for Infertile Men

Platelet Rich Plasma Testis

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: Stanford University · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Investigate the effect of intratesticular injection of autologous platelet rich plasma (PRP) on sperm retrieval rates and IVF outcomes in infertile men who already underwent a negative sperm retrieval. Currently, there is no alternative treatment after failed TESE. Prior series suggest that intratesticular PRP injections may improve TESE outcomes. We hope to determine whether PRP is an effective treatment for this patient population.

Conditions

• Male Infertility
• Nonobstructive Azoospermia
• Azoospermia

Interventions

Type	Name	Description
BIOLOGICAL	Platelet rich plasma	Patients will undergo a blood draw (12 tsp) to prepare the PRP infusion. The use of a centrifuge and an Arteriocyte Magellan kit are necessary for the PRP preparation. After injection of local anesthesia, PRP will be injected into each testicle. * On the third month after the testicular PRP procedure, a TESE will be performed * If the procedure is successful a new IVF cycle using the sperm procured from the procedure will be done.

Timeline

• Start date: 2023-01-18
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2022-07-29
• Last updated: 2026-01-13

Locations

1 site across 1 country: United States