NCT05464563

Study by Electroencephalography of the Link Between the Lack of Self-compassion and the Disorder of Empathy in Schizophrenia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Centre Hospitalier Henri Laborit · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This research project focuses on a fundamental element of the psychopathology of schizophrenia, that is to say, the disorders of self-awareness and on the functional alterations associated with it, that is to say, self-compassion deficit and empathy disorder. It will be a question of better understanding the neuro-functional mechanisms which underlie the lack of self-compassion and the disorder of empathy in schizophrenia, the relationship that these disorders maintain between them but also the relationship that they maintain with the general psychopathology of schizophrenia and, in particular, with the abnormalities of the self. In other words, the overall framework of this project is that of the link between the psychopathology of schizophrenia and the functional impairment associated with it. Its specific field of application is that of the link between self-awareness disorders, self-compassion deficit and empathy disorder. For this, this project proposes a methodological approach combining the recording of intrinsic and extrinsic brain activity using high-density electroencephalography (EEG).

Detailed description

This study includes patients (n=30) and healthy volunteers (n=30). At inclusion visit, participants have: * a psychiatric evaluation; * self evaluation of: empathy, self-compassion, émotionnel processing, anxiety, insight, perceptual aberration and quality of life; * training to practise of self-compassion and empathy (for patients only). During the phase of experimentation, the participants have electroencephalogram exams during a rest phase, a self-compasion task and an empathy task.

Conditions

• Schizophrenia
• Schizoaffective Disorder

Interventions

Type	Name	Description
DEVICE	Electroencephalogram	An electroencephalogram is recorded during a task of rest then self-compassion and then empathy.

Timeline

• Start date: 2022-03-22
• Primary completion: 2024-01-01
• Completion: 2024-01-01
• First posted: 2022-07-19
• Last updated: 2024-08-20

Locations

1 site across 1 country: France