NCT05457491

Novel Antiaging Regenerative Skin Care Regimen Containing Human Platelet Extract (HPE)

• Status: Terminated
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 56 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The Researchers are trying to study a cosmetic skin care product called human platelet extract (HPE) to see if it can be used as a possible treatment for skin anti-aging and skin rejuvenation. They are trying find out the safety and tolerability of topical HPE after multiple doses of topical administration

Conditions

• Skin Aging

Interventions

Type	Name	Description
BIOLOGICAL	Human platelet extract (cosmetic product)	A leukocyte depleted allogeneic product derived from human U.S. sourced pooled apheresed platelets (derived from screened healthy donors). Applied to face twice daily for 12 weeks.
OTHER	Vanicream Gentle Facial Cleanser	A mild cleanser specifically formulated for daily facial use. Applied to face twice daily for 12 weeks
OTHER	EltaMD UV Daily Broad-Spectrum SPF 40	A daily moisturizer with a lightweight formula that provides broad-spectrum sunscreen protection. EltaMD UV Daily Broad-Spectrum SPF 40 provides powerful protection against the sun's harmful UV rays, as it hydrates and is gentle enough for post-procedure skin. Powered by hyaluronic acid, this face sunscreen plumps the skin with lightweight moisture, while micronized zinc and octinoxate shield skin from UVA/UVB rays to prevent the visible signs of environmentally caused aging. Applied to face once daily for 12 weeks.
OTHER	EltaMD PM Therapy Facial Moisturizer	A fortifying face moisturizer to repair elasticity and vitality. EltaMD PM Therapy Facial Moisturizer restores youthfulness while strengthening the skin's natural moisture barrier. Niacinamide blends with antioxidants to boost the skin color and tone, as it speeds up the skin's repair processes. Rice protein peptides aid in encouraging cell growth, promoting collagen formation and improving elasticity. Applied to face once daily for 12 weeks.
OTHER	Vanicream Lite Lotion	Lotion to restore and maintain a normal moisture level. Applied to face twice daily for 12 weeks.

Timeline

• Start date: 2021-10-01
• Primary completion: 2022-07-07
• Completion: 2022-07-07
• First posted: 2022-07-14
• Last updated: 2024-10-04
• Results posted: 2024-10-04

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study