NCT05448534

Electroencephalographic Patterns of Septic Patients and Its Correlation With Cognitive Outcomes

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 160 (actual)
• Sponsor: Hospital Sao Domingos · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators evaluated the electroencephalographic pattern by the Sinek and Young scales during ICU stay and its correlation with cognitive impairment determined by the Montreal Cognitive Assessment (MOCA) in septic patients after 3 months of ICU discharge..

Detailed description

The investigators prospectively evaluate patients with sepsis and septic shock expected to stay in the intensive care unit (ICU) for at least 4 days. We used Sinek and Young scales to classify electroencephalographic patterns during ICU stay (in the first 24 hours after admission and in the third ICU day) and correlate with cognitive outcome evaluated with MOCA score 3 months after ICU discharge. The investigators evaluate as primary outcome the association between electroencephalographic abnormalities and cognitive dysfunction measured by the Montreal Cognitive Assessment (MoCA) 3 months after ICU discharge and secondary outcomes as association between electroencephalographic patterns and 28 days mortality, Quality of Life (SF-36) after 3 months of discharge, ventilator free days, vasoactive drug free days and Glasgow outcome scale.

Conditions

• Sepsis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Eletroencephalography	We used Sinek and Young Scale to classify electroencephalographic patterns and cognitive outcome with MOCA score.

Timeline

• Start date: 2021-11-01
• Primary completion: 2022-11-30
• Completion: 2023-02-24
• First posted: 2022-07-07
• Last updated: 2023-02-28

Locations

1 site across 1 country: Brazil