NCT05443841

Value of Pleural Lavage Cytology in Resectable Esophageal Carcinoma Eastern Cooperative Thoracic Oncology Projects 2005, ECTOP-2005)

A Prospective Study for Pleural Lavage Cytology in Patients With Esophageal Cancer

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 385 (estimated)
• Sponsor: Fudan University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Disease recurrence and metastasis are common after curative treatment for patients with esophageal cancer. Thus, it is important to identify the risk factors to predict disease recurrence and metastasis. Pleural lavage cytology (PLC) is reported to be associated with disease recurrence and patient survival in lung cancer, but the value is unclear in esophageal cancer. The aim of this study is to evaluate the value of PLC in esophageal cancer patient in terms of frequencies, association with patient survival, and efficacy of postoperative treatment.

Detailed description

Pleural lavage cytology will be performed before esophageal resection, and after resection, respectively. Frequency of positive pleural lavage cytology will be determined, and the value of pleural lavage cytology for patients with resectable esophageal cancer will be studied.

Conditions

• Esophageal Cancer

Interventions

Type	Name	Description
OTHER	pleural lavage	pleural lavages before tumor resection and after tumor resecion, respectively

Timeline

• Start date: 2022-07-18
• Primary completion: 2024-07-01
• Completion: 2027-07-01
• First posted: 2022-07-05
• Last updated: 2023-07-13

Locations

11 sites across 1 country: China