NCT05440890

Early Treatment Based Neuroscience Education in Knee

Early Treatment Based Neuroscience Education in Anterior Cruciate Ligament Repair Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 29 (actual)
• Sponsor: University of Malaga · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Determine the effecttiveness of a cross-education strength training protocol in a group of subjects with an anterior cruciate ligament surgery.

Detailed description

The cross-education (CE) phenomenon has been studied in recent years as a form of gain muscle strength not only in healthy subjects but also in acute injuries such as musculoskeletal disorders and immovilitations. Unilateral training of the not injured limb has been suggested as an option to produce cross-edutation in terms of strength and skills. In addition, functional magnetic resonance imaging have been postulated as a promising tool to study the mechanisms of transfer. In the context of our study, arthrogenic muscle inhibition (AMI) of knee extensors is a common consequence after ACL repair in which a CE strength training can lead to reduce quadriceps atrophy and its implications in long terms achievements. Thus, an unilateral strength protocol of the uninjuried limb, according to the last Delphi Consensus, will be run for 10 weeks to check the possible benefits of the transfer in a sample of ACL repair.

Conditions

• Anterior Cruciate Ligament Rupture
• Anterior Cruciate Ligament Injuries

Interventions

Type	Name	Description
OTHER	Best current rehabilitation protocol	Inflamation control and edema with physical agents, recover full pasive and active range of motion, normalize gait pattern, lower limb strengthening (specially quadriceps and hamstrings), neuromuscular control training, cycling, landings and running.
OTHER	Cross-training protocol	Beginning on 2º week after ACLR, 2 times per week during 10 weeks, based on isotonic exercise in leg extension and leg press.

Timeline

• Start date: 2025-04-01
• Primary completion: 2025-05-01
• Completion: 2026-02-01
• First posted: 2022-07-01
• Last updated: 2026-04-08

Locations

1 site across 1 country: Spain