Trials / Not Yet Recruiting
Not Yet RecruitingNCT05428371
Assessment the Cancer Risk of Indeterminate Thyroid Nodules Through Integration of Clinical, Ultrasonographic and Multiomic Features
A Novel, Multimodal, Machine-learning Grounded Approach to Assess the Oncological Risk of Indeterminate Thyroid Nodules
- Status
- Not Yet Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 256 (estimated)
- Sponsor
- University of Cagliari · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Indeterminate thyroid nodules have a mild risk of malignancy (15-30%). The aim of our study is to individuate new biomarkers of thyroid carcinoma through multiomic analyses of blood samples and of specimen samples of patients with indeterminate thyroid nodules.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Multiomic analyses of blood and surgical specimens | The following items will be evaluated: * cell free dna length and integrity * presence or absence of SNPs in cfDNA and in DNA extracted from surgical samples * qualitative and quantitative evaluation of serum and surgical specimens proteome (proteomics) |
Timeline
- Start date
- 2023-01-01
- Primary completion
- 2027-05-31
- Completion
- 2027-12-31
- First posted
- 2022-06-23
- Last updated
- 2022-06-23
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT05428371. Inclusion in this directory is not an endorsement.