Clinical Trials Directory

Trials / Completed

CompletedNCT05419388

A Study of Multiple Doses of RO7247669 in Participants With Previously Untreated Unresectable or Metastatic Melanoma

A Randomized, Open-Label, Multicenter, Phase II Study of Multiple Doses of RO7247669 in Participants With Previously Untreated Unresectable or Metastatic Melanoma

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
93 (actual)
Sponsor
Hoffmann-La Roche · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess the efficacy, safety, pharmacokinetics (PK), and pharmacodynamics of two dose levels of RO7247669 in participants with unresectable or metastatic melanoma to select the recommended dose for further development.

Conditions

Interventions

TypeNameDescription
DRUGRO7247669Participants will receive intravenous (IV) RO7247669 Q3W

Timeline

Start date
2022-08-15
Primary completion
2024-05-01
Completion
2025-11-27
First posted
2022-06-15
Last updated
2026-02-04

Locations

22 sites across 10 countries: Australia, Brazil, Canada, Czechia, Greece, New Zealand, Poland, Slovakia, Spain, Turkey (Türkiye)

Regulatory

Source: ClinicalTrials.gov record NCT05419388. Inclusion in this directory is not an endorsement.