NCT05401604

Probiotic Beer to Enhance Gut Health and Immune System Function

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: National University of Singapore · Academic / Other
• Sex: Male
• Age: 21 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This study investigates the immunological and gut microbiome effects of moderate probiotic beer consumption.

Detailed description

Studies have shown that moderate alcohol consumption and probiotics have each shown immunomodulatory anti-inflammatory effects. However, to our knowledge, the effect of adding a probiotic strain to a beer drink, together with moderate alcohol consumption, on immunity and gut microbiome has yet to be studied. The probiotic beer used in this study taps on this unexplored research area and may potentially serve as a more healthful option to consumers than normal beer in the future, given the vast popularity of this beverage and probiotics.

Conditions

• Inflammation
• Nutrition, Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Moderate probiotic beer consumption	Consumption of one can of probiotic beer per day for 14 days. Blood and fecal samples will be collected at the start and end of the intervention to analyse for immunological biomarkers and gut microbiome.
DIETARY_SUPPLEMENT	Moderate normal beer consumption	Consumption of one can of normal beer per day for 14 days. Blood and fecal samples will be collected at the start and end of the intervention to analyse for immunological biomarkers and gut microbiome.

Timeline

• Start date: 2021-08-27
• Primary completion: 2022-02-18
• Completion: 2022-02-18
• First posted: 2022-06-02
• Last updated: 2022-06-02

Locations

1 site across 1 country: Singapore