NCT05379010

Endodontic Microsurgery With the Use of L-PRF Block

Endodontic Microsurgery With the Use of L-PRF Block: a Randomized Controlled Clinical Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Universitaire Ziekenhuizen KU Leuven · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study evaluates the effect of leucocyte and platelet rich fibrin Block (L-PRF Block) during endodontic microsurgery (EMS) on patient's post-operative comfort and periapical bone healing in large peri-apical lesions.

Detailed description

This study evaluates the effect of leucocyte and platelet rich fibrin Block (L-PRF Block) during endodontic microsurgery (EMS) on patient's post-operative comfort and periapical bone healing in large peri-apical lesions. The trial design is an open randomized controlled clinical trial with two groups. Half of the participants will receive EMS with L-PRF Block (experimental group), the other half without (control group).

Conditions

• Apical Periodontitis
• Apical Periodontal Cyst

Interventions

Type	Name	Description
PROCEDURE	Endodontic Microsurgery	Surgical removal of 3 millimeters of the root-end, removal of the apical pathology, Root-end preparation and retrograde filling. The entire procedure is done under magnification.

Timeline

• Start date: 2020-08-03
• Primary completion: 2024-10-31
• Completion: 2024-10-31
• First posted: 2022-05-18
• Last updated: 2023-09-15

Locations

1 site across 1 country: Belgium