NCT05376098

An fNIRS Study of Motor Cortical Activation in Stoke Patients

A Temporal Study of Brain Motor Regions of Acute Ischemic Stroke Based on fNIRS

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Xuanwu Hospital, Beijing · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The investigators evaluate the activation and connectivity of patients' motor regions in the acute phase of ischemic stroke by fNIRS.

Detailed description

This study aims to analyze the progress of brain recovery from upper-limb deficit due to acute ischemic stroke, using Functional Near-infrared Spectroscopy(fNIRS) as the main neural imaging method. Fifty patients having experienced a stroke onset within seven days will be recruited from the emergency room. The fNIRS signals will be recorded bilaterally over the contralateral sensorimotor cortex, the premotor area, the supplementary motor area, the primary motor cortex for 14 days after being diagnosed. Then compute activation and connectivity of the regions. The motor function data measured by the assessment scales, as well as the behavioral record during the fNIRS motor tasks will be collected as well.

Conditions

• Acute Ischemic Stroke

Timeline

• Start date: 2022-02-01
• Primary completion: 2024-07-01
• Completion: 2024-07-31
• First posted: 2022-05-17
• Last updated: 2022-05-17

Locations

1 site across 1 country: China