NCT05333900

Dietary Impact on Intestinal Sulfate Metabolism

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: University of Minnesota · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This is a 5-week crossover pilot study of 15 highly motivated healthy volunteers who will consume two 7-day intervention diets: 1) a diet low in sulfur-containing amino acids (Low-S diet), emphasizing plant-based foods and fat sources; and 2) a diet high in sulfur-containing amino acids (High-S diet), emphasizing animal protein and fat sources. A 14-day washout period will follow each intervention, in which participants will eat their typical diets.

Conditions

• Healthy Nutrition

Interventions

Type	Name	Description
BEHAVIORAL	Plant-Based Diet then animal-based diet	Participants started with plant based diet: high in fiber, low in animal products for 7 days, with 14 day washout period between interventions. Following that, participants were switched to animal-based diet: high in animal products, low in fiber for 7 days.
BEHAVIORAL	Animal-based diet then plant-based diet	Participants were started with animal-based diet: high in animal products, low in fiber for 7 days, with 14 days washout period between interventions. Following that, participants were switched to plant-based diet: high in fiber, low in animal products for 7 days

Timeline

• Start date: 2016-12-07
• Primary completion: 2020-12-31
• Completion: 2021-03-18
• First posted: 2022-04-19
• Last updated: 2023-12-05
• Results posted: 2023-12-05

Locations

1 site across 1 country: United States