Clinical Trials Directory

Trials / Unknown

UnknownNCT05313490

Exercise Fatiguability in Older Adults: The Protective Effects of Dietary Nitrate Supplementation

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
40 (estimated)
Sponsor
Marquette University · Academic / Other
Sex
All
Age
60 Years – 90 Years
Healthy volunteers
Accepted

Summary

Vascular and skeletal muscle function decline with age and are associated with decreased nitric oxide (NO) bioavailability. Dietary nitrate supplementation in the form of beet root juice increases NO bioavailability and improves exercise tolerance in younger adults, yet its effects on fatigability in older adults are largely unknown. The proposed research will investigate the impact of increased NO bioavailability on vascular function, skeletal muscle bioenergetics, and fatigability in older (≥65 yrs) men and women.

Conditions

Interventions

TypeNameDescription
DIETARY_SUPPLEMENTBeetroot Juice7 days of 140 mL per day of beetroot juice
OTHERPlacebo Beetroot Juice7 days of 140 mL per day of placebo beetroot juice

Timeline

Start date
2022-05-01
Primary completion
2023-12-31
Completion
2023-12-31
First posted
2022-04-06
Last updated
2022-08-24

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT05313490. Inclusion in this directory is not an endorsement.