Trials / Active Not Recruiting
Active Not RecruitingNCT05301036
Personalized Ultrasonic Brain Stimulation for Depression
Personalized Ultrasonic Brain Stimulation for Depression: A Pilot Study of Target Engagement and Mood Effects
- Status
- Active Not Recruiting
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- Sponsor
- University of Utah · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
This study will evaluate a new form of non-invasive brain stimulation for individuals with depression. Personalized low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation parameters during psychological and physiological monitoring. A well-tolerated stimulation protocol will then be selected for subsequent testing in a blinded randomized sham-controlled cross-over trial to evaluate brain target engagement using magnetic resonance imaging.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Diadem prototype | Diadem prototype device delivers personalized low-intensity transcranial focused ultrasound stimulation |
Timeline
- Start date
- 2022-07-15
- Primary completion
- 2024-07-14
- Completion
- 2024-12-14
- First posted
- 2022-03-29
- Last updated
- 2024-08-09
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05301036. Inclusion in this directory is not an endorsement.