Clinical Trials Directory

Trials / Completed

CompletedNCT05298085

Effect of Intranasal Oxytocin on Dysphagia in Children and Adolescents With Prader-Willi Syndrome

Effect of Intranasal Oxytocin on Dysphagia Related to Oropharyngo-oesophageal Dysmotility in Children and Adolescents With Prader-Willi Syndrome: a Phase 2B Study

Status
Completed
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
25 (actual)
Sponsor
University Hospital, Toulouse · Academic / Other
Sex
All
Age
2 Years – 17 Years
Healthy volunteers
Not accepted

Summary

This phase 2B is designed to test the effectiveness of intranasal Oxytocin on Prader Willi Syndrome (PWS). This is a prospective, multicentre, randomised, double-blind, Phase 2B clinical study planned to include around 24 PWS patients aged 2-17 years and 5 months.

Conditions

Interventions

TypeNameDescription
DRUGOxytocin nasal sprayStudy treatment will be administered intranasally daily for 12 weeks. The daily dose of OT will be adapted according to age at the beginning of the study
DRUGPlaceboStudy treatment will be administered intranasally daily for 12 weeks.

Timeline

Start date
2022-04-05
Primary completion
2023-04-11
Completion
2023-04-11
First posted
2022-03-28
Last updated
2023-06-01

Locations

4 sites across 1 country: France

Regulatory

Source: ClinicalTrials.gov record NCT05298085. Inclusion in this directory is not an endorsement.