NCT05295576

Effect of Non Surgical Periodontal Therapy on Inflammatory Markers in Chronic Periodontitis Patients

Effect of Non Surgical Periodontal Therapy on Levels of Il-17 and Il-18 in Chronic Periodontitis Patients Versus Periodontally Healthy Individuals

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Future University in Egypt · Academic / Other
• Sex: All
• Age: 30 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The current study was performed to study levels of Il-17 and Il-18 in aggressive periodontitis patients before and after non surgical periodontal therapy

Detailed description

Background:host defense factors are involved in pathogenesis of chronic periodontitis so, the current study is assessing levels of Il-17 and Il-18 in chronic periodontitis patients versus periodontally healthy controls. Subjects and methods: Fifty subjects were included; twenty five of them are diagnosed with chronic periodontitis patients and twenty five are periodontally healthy subjects. Probing depth (PD), clinical attachment level (CAL), plaque index (PI) and gingival index (GI) were recorded for all the enrolled subjects. GCF levels of Il-17 and IL-18 were analyzed by enzyme-linked immunosorbent assay (ELISA).

Conditions

• Aggressive Periodontitis

Interventions

Type	Name	Description
PROCEDURE	non surgical periodontal therapy	Scaling and root planing

Timeline

• Start date: 2021-03-27
• Primary completion: 2021-12-15
• Completion: 2021-12-30
• First posted: 2022-03-25
• Last updated: 2022-03-25

Locations

1 site across 1 country: Egypt