NCT05288764

Effect of Ketamine on BIS Values

Correlation Between Concentration at the Effector Site of Ketamine (Calculated With DOMINO Pump) and Bispectral Index Values During General Anaesthesia for Breast Surgery.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 14 (actual)
• Sponsor: University of Padova · Academic / Other
• Sex: Female
• Age: 18 Years – 90 Years
• Healthy volunteers: —

Summary

Aim of this trial is to define if Concentration at the effector site (Ce) of Ketamine, calculated with DOMINO model infusion pump are correlated with Bispectral Index BIS values during general anaesthesia for breast surgery.

Detailed description

Correlation between Concentration at the effector site (Ce) of Ketamine and Bispectral Index (BIS) values during general anaesthesia for breast surgery has not been defined yet. We want to analyze this correlation during general anaesthesia conducted using Propofol, ketamine and remifentanil. All of these drugs will be delivered with Targeted-ControlledInfusion pumps (in particular Eleveld for Propofol, Minto for Remifentanil and Domino for Ketamine).

Conditions

• Anesthesia Brain Monitoring
• Ketamine

Interventions

Type	Name	Description
DEVICE	Bispectral Index	Comparing Bispectral index values (usually adopted during general anaesthesia monitoring) to Ketamine concenetration at the effector site calculated with Domino model pump (usually adopted for Ketamine infusion during general anaesthesia)

Timeline

• Start date: 2022-03-31
• Primary completion: 2023-01-15
• Completion: 2023-01-30
• First posted: 2022-03-21
• Last updated: 2023-06-13

Locations

1 site across 1 country: Italy