NCT05283733

Open to Laparoscopic Reverse Conversion of Perforated Appendicitis

A Prospective Randomized Controlled Trial of Reverse Conversion (Open to Laparoscopic) in Management of Acute Perforated Appendicitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 426 (actual)
• Sponsor: Zagazig University · Other Government
• Sex: All
• Age: 16 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

A Prospective Randomized Controlled Trial of Reverse Conversion (Open to Laparoscopic) in management of Acute Perforated Appendicitis

Detailed description

Introduction: Acute appendicitis (AA), a frequent intra-abdominal surgical pathology, necessitates a thorough awareness of its symptoms, examination, diagnosis, and total surgical management. The surgical approach to AA is appendectomy; nevertheless, the medical literature continues to argue the merits of open vs laparoscopic surgery. As with other laparoscopic surgical techniques, the literature reports lower discomfort, earlier resumption of oral feeding and shorter hospital stay following laparoscopic appendectomy (LA) as compared to open appendectomy (OA). Additionally, laparoscopy has some drawbacks such as greater cost and lengthier operating durations as compared to open surgery. The goal of this clinical study: was to compare open appendectomy versus laparoscopic conversion from open (reverse conversion) for the treatment of acute perforated appendicitis in our setting. Patients and procedures: 426 patients had perforated appendectomy and divided between two groups: group A (interventional) 213 patients who were subjected to the reverse conversion technique and group B (control)213 patients who were operated by the open technique. The key end goals for comparing both groups were the rates of intraabdominal abscess, rates of wound infection, rates of ileus and rates of reoperation. The hospital length of stay and the operative time were used as secondary end goals for comparison.

Conditions

• Laparoscopic Surgery
• Acute Appendicitis With Rupture
• Sepsis
• Abdominal Abscess

Interventions

Type	Name	Description
PROCEDURE	reverse conversion technique	converting open appendectomy to laparoscopic technique for proper control of intraabdominal sepsis

Timeline

• Start date: 2018-01-18
• Primary completion: 2021-12-15
• Completion: 2021-12-25
• First posted: 2022-03-17
• Last updated: 2022-03-17

Locations

1 site across 1 country: Egypt