NCT05277740

Implementation of a Novel Functional Eye-Tracking Biomarker for Multiple Sclerosis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 120 (estimated)
• Sponsor: McGill University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This study aims to develop and validate a sensitive and non-invasive eye-tracking software application. This study will obtain participant responses to brief cognitive tests designed to evaluate several key functions known to be affected by CIS and RRMS and non-invasive eye movement measurements in response to visually presented stimuli during specifically designed eye-tracking tests. The study data will be used to develop machine learning algorithms and validate a software application intended to identify which metrics-or combination thereof-can serve as reliable biomarker of CIS and RRMS disease progression and cognitive status.

Conditions

• Clinically Isolated Syndrome
• Relapsing Remitting Multiple Sclerosis

Interventions

Type	Name	Description
DEVICE	Eye-tracking	Eye-tracking technology and algorithms used to successfully capture and track eye movements using an electronic tablet and the embedded camera of the device.

Timeline

• Start date: 2022-09-01
• Primary completion: 2024-07-01
• Completion: 2024-07-01
• First posted: 2022-03-14
• Last updated: 2023-11-09

Locations

1 site across 1 country: Canada