Trials / Active Not Recruiting
Active Not RecruitingNCT05267509
An Integrated Radio-immunological Approach
Identification of the Immuno Suppressive Characteristics of Glioma Patients by an Integrated Radio-immunological Approach
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 31 (actual)
- Sponsor
- Istituto Oncologico Veneto IRCCS · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The most aggressive primary brain tumors in adults, glioblastomas, are characterized by a profound local and systemic immune suppression. During tumor progression, the infiltration of inflammatory leukocytes, especially of myeloid origin, endowed with immunosuppressive function is observed. Aim of this study is to evaluate myeloid cell infiltrate and iron metabolism in tumor-associated macrophages by combining a multimodal MRI imaging technique with immunophenotyping of the tumor microenvironment.
Conditions
Timeline
- Start date
- 2022-02-23
- Primary completion
- 2025-06-30
- Completion
- 2026-12-31
- First posted
- 2022-03-04
- Last updated
- 2026-01-23
Locations
2 sites across 1 country: Italy
Source: ClinicalTrials.gov record NCT05267509. Inclusion in this directory is not an endorsement.