NCT05259501

Remote Methadone Ingestion Surveillance Trial (RMIST)

Remote Methadone Ingestion Surveillance Trial (RMIST): A Novel and Practical Opioid Use Disorder Treatment Approach During and After the COVID-19 Pandemic

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: University of Texas Southwestern Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The Remote Methadone Ingestion Surveillance Trial (RMIST) will explore a potential method of methadone ingestion surveillance that may mitigate patient safety risks of take-home methadone treatment regimens while minimizing the risk of diversion and evaluating the acceptability and feasibility of these monitoring methods. The method utilizes an innovative existing technology.

Detailed description

The Remote Methadone Ingestion Surveillance Trial (RMIST) aims to evaluate the performance and acceptability of a remote methadone ingestion surveillance that may mitigate the patient safety risks of take-home methadone treatment regimens for opioid use disorder (OUD) while minimizing the risk of diversion. Data describing the monitoring performance and patient acceptability of the method will inform investigators of the feasibility of using remote surveillance technology to monitor medication for OUD and mitigate treatment barriers. This study will lay the groundwork for a safe and robust remotely monitored methadone treatment platform that addresses long-standing accessibility and acceptability barriers to treatment for OUD.

Conditions

• Opioid Use Disorder

Interventions

Type	Name	Description
OTHER	RMIST	RMIST will involve: 1. A study automated visual recognition web-based platform accessible on the participant's smartphone web browser. 2. A supply of methadone in single use bottles and previously described packaging to be kept securely at the methadone clinic/lab setting.

Timeline

• Start date: 2025-01-15
• Primary completion: 2025-03-13
• Completion: 2025-03-13
• First posted: 2022-02-28
• Last updated: 2025-12-23

Locations

1 site across 1 country: United States