NCT05234203

The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Big Bold Health, PBC · Industry
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Accepted

Summary

This is a prospective, interventional, single-arm, open-label pilot study of 50 patients to evaluate the effect of a polyphenol-rich nutritional supplement on epigenetic and cellular markers of immune age.

Detailed description

The objective of this study is to understand the impact of a polyphenol-rich supplement on measurements of epigenetic immune age and immune cell patterns germane to immune age over a 90-day period. The primary objective of this trial is to assess the effects of the supplement, HTB Rejuvenate™, on immune age markers. The secondary objective of this trial is to assess the effects of the supplement, HTB Rejuvenate, on leukocyte immune profiles including T cell subsets and granulocytes.

Conditions

• Immunity Disorders
• Aging
• Inflammation

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	HTB Rejuvenate	90 days of BID dosing of 2 capsules of HTB Rejuvenate

Timeline

• Start date: 2022-03-25
• Primary completion: 2022-10-07
• Completion: 2022-10-07
• First posted: 2022-02-10
• Last updated: 2022-12-06

Locations

1 site across 1 country: United States