NCT05217485

Continuous Ambulatory Cardiac Monitoring for Recurrent Atrial Fibrillation After Sepsis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 125 (estimated)
• Sponsor: Cambridge University Hospitals NHS Foundation Trust · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

To detect atrial fibrillation after infection.

Detailed description

This study will prospectively recruit patients who are admitted to CUH general medical wards due to an infection or sepsis and develop new/first diagnosed transient AF. In CUH, our previous projects have shown that around 1500 patients are admitted under general medicine each month at least 1 new diagnosis of AF is made each day (30/month)26. In particular to the cohort that develop sepsis, they may well be frail and elderly where anticoagulation is often not prescribed as a result 27 unless definitive diagnosis of recurrent AF would be made. The CAMS-AF study will closely tie in with an already existing stroke prevention service at CUH (SOS-AF) who are already screening for patient admitted with AF on general medical wards and will therefore be able to identify those with new AF during an episode of sepsis. Potential participants will be approached by the study investigators prior to discharge and if they are in sinus rhythm written consent will be obtained to place a non-invasive wearable cardiac monitor patch for 14-days, to detect any subclinical arrhythmias, particularly AF.

Conditions

• Atrial Fibrillation
• Sepsis
• Infections
• Cardiac Arrhythmia

Interventions

Type	Name	Description
DEVICE	Zio 14-day cardiac patch	A wearble adhesive cardiac patch (14-day) called Zio

Timeline

• Start date: 2022-03-01
• Primary completion: 2023-03-01
• Completion: 2024-03-01
• First posted: 2022-02-01
• Last updated: 2022-02-01

Locations

1 site across 1 country: United Kingdom