NCT05195021

The Effect of Different Irrigation and Disinfection Methods on Post-operative Pain (PP)

The Effect of Different Irrigation and Disinfection Methods on Post-operative Pain in Mandibular Molars With Symptomatic Apical Periodontitis: A Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Biruni University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Aim: The aim of this study was to examine post-operative pain (PP) severity after conventional irrigation and sonic activation methods, with and without laser disinfection in mandibular molar teeth diagnosed with symptomatic apical periodontitis. Methods: In total, 80 patients with symptomatic apical periodontitis were included in this randomized clinical study. There were four different irrigation and disinfection groups. In group 1, conventional irrigation only was applied. In group 2, EDDY (VDW, Munich, Germany), a sonic irrigation activation system, was applied. In groups 3 and 4, irradiation with a 980-nm diode laser was performed, following irrigation with the conventional method (needle irrigation) and EDDY (VDW) irrigation system, respectively. PP was assessed using a visual analogue scale (VAS). The patients were instructed to record their PP using this scale 8, 24, 48 hours and 7 days post-procedure, in addition to their analgesic intake. A chi-square test, Fisher's exact chi-square test and Fisher-Freeman-Halton exact test were used to assess qualitative data. Inter-group and intra-group parameters were assessed using the Kruskal-Wallis test and Wilcoxon's test at a significance level of p \< 0.05 (for both).

Conditions

• Post-operative Pain
• Apical Periodontitis

Interventions

Type	Name	Description
DEVICE	EDDY	EDDY (VDW) sonic irrigation activation system
DEVICE	Diode Laser device	980-nm diode laser device
DEVICE	Conventional irrigation	Conventional root canal irrigation with 31-guage side port needle

Timeline

• Start date: 2020-12-01
• Primary completion: 2021-06-30
• Completion: 2021-07-30
• First posted: 2022-01-18
• Last updated: 2022-01-18

Locations

1 site across 1 country: Turkey (Türkiye)