NCT05176171

Surface Ablation With Corneal Cross Linking in Mild Keratoconus

Advanced Surface Ablation With Corneal Cross Linking in Mild Keratoconus

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Shahid Beheshti University · Academic / Other
• Sex: All
• Age: 30 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Interventional and comparative prospective study: Sixty-nine eyes (38 patients) suffering from keratoconus (stages 1-2 Amsler-Krumeich classification) will be divided into four groups. The four groups underwent topography- and non-topography-guided PRK with sequential and simultaneous CXL. The main outcome measures will be pre-and postoperative uncorrected distance visual acuity (UDVA), best-corrected distance visual acuity (CDVA), manifest refraction, contrast sensitivity, and keratometry

Conditions

• Keratoconus
• Corneal Cross-Linking

Interventions

Type	Name	Description
PROCEDURE	Photorefractive Keratectomy with Corneal Cross-Linking	To our knowledge, this study is one of the first to compare the visual results of non-topography-guided and topography-guided photorefractive keratectomy (PRK) applying sequential and simultaneous corneal cross-linking (CXL) treatment for keratoconus. Considering recent advances in cross-linking and imaging in keratoconus, the outcomes of this study can lead us to several non-invasive algorithm management options.

Timeline

• Start date: 2018-03-05
• Primary completion: 2019-03-05
• Completion: 2023-07-05
• First posted: 2022-01-04
• Last updated: 2022-04-18

Locations

1 site across 1 country: Iran